Utilizing biodegradable alloys as guided bone regeneration (GBR) membrane: Feasibility and challenges

Guided bone regeneration (GBR) is a therapeutic procedure used to enhance alveolar volume before dental implants. Commercial non-absorbable membranes (i.e., titanium membranes) typically require second surgery remove, whereas absorbable collagen will fail when put over extensive lesions due their low mechanical strength. The GBR membrane that has been sought still being developed. Biodegradable metals (BMs), particularly Mg and Zn, have recently postulated as promising barrier candidates. Herein, the goal of this research evaluate biological feasibility using BMs membranes. It shows wide range potential applications membranes, owing benign biocompatibility, sufficient support, tunable degradation rate, good osteogenic capabilities, broad-spectrum antibacterial behavior, improved wound healing ability. rapid hydrogen evolution impact, stress corrosion cracking behavior all pose obstacles use Mg-based which can be by surface modifications, heat treatment, alloying, etc. Due its acceptable rate lack gas production, Zn appears better candidate for usage membrane. In general, advances in development paved door oral clinical trials.